أ.د. عادل أحمد علي سعيد المنصب الأكاديمي: أستاذ الصيدلانيات والصيدلة الصناعية مناصب أخري: - وكيل الكلية لشؤون التعليم والطلاب - وكيل الكلية لشؤون خدمة المجتمع وتنمية البيئة (سابقا) - رئيس قسم الصيدلانيات والصيدلة الصناعية (سابقا) الأتصال: adel.ali@pharm.bsu.edu.eg الدرجات العلمية: 2008 دكتوراة في الصيدلانيات والصيدلة الصناعية كلية الصيدلة جامعة القاهرة مصر 2005 ماجيستير في الصيدلانيات والصيدلة الصناعية كلية الصيدلة جامعة القاهرة مصر 2001 بكالوريوس في العلوم الصيدلية كلية الصيدلة جامعة القاهرة مصر عنوان رسالة الماجستير: دراسة صيدلية علي عقار البنتوكسـفيللين منضبط الانطلاق في أشكـال صـيدلية صـلبة A Pharmaceutical Study on Controlled Release Pentoxifylline in Solid Dosage Forms عنوان رسالة الدكتوراه: دراسة صيدلية على بعض العقاقير المضادة للذبحة الصدرية A pharmaceutical Study on Extended Release Solid Dosage Forms of certain Antianginal Drugs المهام التدريسية: - صيدلة فيزيائية - صيدلانيات 2 - صيدلانيات 3 - صيدلانيات 4 - اشكال صيدلية 1 - اشكال صيدلية 2 - اشكال صيدلية 3 أبحاث مختارة: 1. El Sisi, A.M., Eissa, E.M., Hassan, A.H., Bekhet, M.A., El-Ela, F.I.A., Roh, E.J., Kharshoum, R.M. and Ali, A.A., 2025. Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies. Pharmaceuticals, 18(1), p.46. 2. Hendawy, O.M., Elkomy, M.H., Ali, A.M.A., Zaki, R.M., Aldosari, B.N., Ali, A.A., Elhabal, S.F. and Eid, H.M., 2025. Nose-to-Brain Delivery of Armodafinil Loaded Spanlastics in Situ Gel: Formulation, Statistical Optimization, and Pharmacokinetics Evaluation. Journal of Pharmaceutical Innovation, 20(6), pp.1-16. 3. Elkomy, M.H., Hendawy, O.M., Zaki, R.M., Tulbah, A.S., Aldosari, B.N., Ali, A.A. and Eid, H.M., 2025. Intranasal trimethyl chitosan-coated emulsomes containing tizanidine as brain-targeted therapy in spasticity: formulation, optimization, and pharmacokinetic assessment. Drug Delivery and Translational Research, 15(7), pp.2565-2580. 4. Eid, H.M., Ali, A.A., Salama, A.H., Galal, A.F., Fouad, S.A. and Moubarak, G.A., 2026. Development of Novel Olmesartan Medoxomil Loaded Leciplex for Enhanced Oral Bioavailability: Formulation, Histopathological Analysis, and In Vivo Pharmacokinetic Studies. Journal of Pharmaceutical Innovation, 21(1), p.37. 5. Eissa, E.M., El Sisi, A.M., Bekhet, M.A., El-Ela, F.I.A., Kharshoum, R.M., Ali, A.A., Alrobaian, M. and Ali, A.M.A., 2024. pH-Sensitive In Situ Gel of Mirtazapine Invasomes for Rectal Drug Delivery: Protruded Bioavailability and Anti-Depressant Efficacy. Pharmaceuticals, 17(8), p.978. 6. Aboud, H.M., El Menshawe, S.F., Mohammed, N.H., Tulbah, A.S. and Ali, A.A., 2024. Optimization and Appraisal of Nintedanib-Loaded Mixed Polymeric Micelles as a Potential Nanovector for Non-Invasive Pulmonary Fibrosis Mitigation. Pharmaceuticals, 17(10), p.1275. 7. Eid, H.M., Turkia, T.H., Ali, A.A. and Aboud, H.M., 2024. A Novel Chitosan-coated Leciplex Loaded with Ambrisentan as a Possible Pulmonary Nanosystem: Optimization, Characterization, and Pharmacokinetics Assessments. Journal of Pharmaceutical Sciences. 8. Salem, H.F., Moubarak, G.A., Ali, A.A., Salama, A.A. and Salama, A.H., 2023. Budesonide-loaded bilosomes as a targeted delivery therapeutic approach against acute lung injury in rats. Journal of Pharmaceutical Sciences, 112(3), pp.760-770. 9. Salem, H.F., Ali, A.A., Rabea, Y.K., El-Ela, F.I.A. and Khallaf, R.A., 2023. Optimization and Appraisal of Chitosan-Grafted PLGA Nanoparticles for Boosting Pharmacokinetic and Pharmacodynamic Effect of Duloxetine HCl Using Box-Benkhen Design. Journal of Pharmaceutical Sciences, 112(2), pp.544-561. 10. Tulbah, A.S., Elkomy, M.H., Zaki, R.M., Eid, H.M., Eissa, E.M., Ali, A.A., Yassin, H.A., Aldosari, B.N., Naguib, I.A. and Hassan, A.H., 2023. Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures. International Journal of Pharmaceutics: X, 6, p.100206. 11. Elkomy, M.H., Ali, A.A. and Eid, H.M., 2022. Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review. Journal of Controlled Release, 351, pp.923-940. 12. Eissa, E.M., Elkomy, M.H., Eid, H.M., Ali, A.A., Abourehab, M.A., Alsubaiyel, A.M., Naguib, I.A., Alsalahat, I. and Hassan, A.H., 2022. Intranasal delivery of granisetron to the brain via nanostructured cubosomes-based in situ gel for improved management of chemotherapy-induced emesis. Pharmaceutics, 14(7), p.1374. 13. Salem, H.F., Nafady, M.M., Ali, A.A., Khalil, N.M. and Elsisi, A.A., 2022. Evaluation of metformin hydrochloride tailoring bilosomes as an effective transdermal nanocarrier. International Journal of Nanomedicine, pp.1185-1201. 14. Salem, H.F., Nafady, M.M., Ali, A.A., Khalil, N.M. and Elsisi, A.A., 2023. Cholate-based nano emulgel of 1, 1-dimethylbiguanide can diminish the liver damage in NAFLD induced by high-fat diet. Journal of Applied Pharmaceutical Science, 13(7), pp.258-269. 15. Bekhet, M.A., Ali, A.A., Kharshoum, R.M., El-Ela, F.I.A. and Salem, H.F., 2022. Intranasal niosomal in situ gel as a novel strategy for improving citicoline efficacy and brain delivery in treatment of epilepsy: In vitro and ex vivo characterization and in vivo pharmacodynamics investigation. Journal of Pharmaceutical Sciences, 111(8), pp.2258-2269. 16. Salem, H.F., Ali, A.A., Rabea, Y.K., El-Ela, F.I.A. and Khallaf, R.A., 2022. Glycerosomal thermosensitive in situ gel of duloxetine HCl as a novel nanoplatform for rectal delivery: in vitro optimization and in vivo appraisal. Drug Delivery and Translational Research, 12(12), pp.3083-3103. 17. Salem, H.F., Ali, A.A., Hegazy, A.M., Sadek, A.R.A. and Aboud, H.M., 2022. Harnessing of doxylamine succinate/pyridoxine hydrochloride-dual laden bilosomes as a novel combinatorial nanoparadigm for intranasal delivery: in vitro optimization and in vivo pharmacokinetic appraisal. Journal of Pharmaceutical Sciences, 111(3), pp.794-809. 18. Ali, A.M.A., Warsi, M.H., Abourehab, M.A. and Ali, A.A., 2022. Preparation and transformation of solid glass solutions of clotrimazole to nanosuspensions with improved physicochemical and antifungal properties. Journal of Pharmaceutical Innovation, 17(4), pp.1420-1433. 19. Eid, H.M., Ali, A.A., Ali, A.M.A., Eissa, E.M., Hassan, R.M., Abo El-Ela, F.I. and Hassan, A.H., 2022. Potential use of tailored citicoline chitosan-coated liposomes for effective wound healing in diabetic rat model. International Journal of Nanomedicine, pp.555-575. 20. Ali, A.A., Hassan, A.H., Eissa, E.M. and Aboud, H.M., 2021. Response surface optimization of ultra-elastic nanovesicles loaded with deflazacort tailored for transdermal delivery: Accentuated bioavailability and anti-inflammatory efficacy. International Journal of Nanomedicine, pp.591-607. 21. Zaki, M.M., Abdelwahab, N.S., Ali, A.A. and Sharkawi, S.M.Z., 2019. Simultaneous determination of bisoprolol fumarate and rosuvastatin calcium in a new combined formulation by validated RP-HPLC. European Journal of Chemistry, 10(1), pp.52-56. 22. Heba M. Aboud, Amira H. Hassan, Adel A. Ali & Abdel-Razik H. Abdel-Razik., "Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting", Drug Delivery, (2018) 25:1, 1328-1339 23. Mohamed H. El komy, Shahira F El-Menshawe, Adel A. Ali, Abdelkhalk Ali Halawa and Ahmed SGSrag El-Din." Betahistine dihydrochloride transdermal delivery via optimized thermosensitive gels: percutaneous absorption evaluation using rat growth as a biomarker"., Drug Delivery and Translational Research (2018): Vol.8, No. 1, pp.165 - 177. 24. Shahira F El-Menshawe, Adel A. Ali, Abdelkhalk Ali Halawa and Ahmed SGSrag El-Din., " A novel transdermal nanoethosomal gel of betahistine dihydrochloride for weight gain control: in-vitro and in-vivo characterization"., Drug Design, Development and Therapy (2017):11, 3377 - 3388. 25. Shahira F El-Menshawe, Adel A. Ali, Mohamed ARabeh and Nermeen M Khalil., "Nanosized soy phytosome-based thermogel as topical anti-obesity formulation: an approach for acceptable level of evidence of an effective novel herbal weight loss product"., International Journal of Nanomedicine (2018):13, 307 - 318. 26. Mohamed O. Mahmoud, Heba M. Aboud, Amira H. Hassan, Adel A. Ali, Thomas P. Johnston., "Transdermal delivery of atorvastatin calcium from novel nanovesicular systems using polyethylene glycol fatty acid esters: Ameliorated effect without liver toxicity in poloxamer 407-induced hyperlipidemic rats". Journal of Controlled Release, 254 (2017) 10 - 22. 27. Fatma A. Moawad, Adel A. Ali, Heba F. Salem., “Nanotransfersomes loaded thermosensitive in situ gel as a rectal delivery system of tizanidine HCl: preparation, in vitro and in vivo performance”. Drug Deliv, 2017; 24(1): 252 - 260. 28. Mohamed A El-Nabarawi, Adel A. Ali, Heba M Aboud, Amira H Hassan and Amany H Godah “Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation”. Drug Design, Development and Therapy (2016):10, 4031 - 4045. 29. Sayed M Ahmed, Adel A. Ali, Ahmed MA Ali, Omiya A Hassan., “Design and in vitro/in vivo evaluation of sustained release floating tablets of itopride hydrochloride”. Drug Design, Development and Therapy (2016):10, 4061 - 4071. 30. Heba M. Aboud, Adel A. Ali, Shahira F. El Menshawe, Ahmed Abd Elbary.,” Nanotransfersomes of carvedilol for intranasal delivery: formulation, characterization and in vivo evaluation”. Drug Delivery, (2016); 23(7): 2471 – 2481 31. Heba M. Aboud, Mohammed H. El komy, Adel A. Ali, Shahira F. El Menshawe and Ahmed Abd Elbary., "Development, Optimization and Evaluation of Carvedilol Loaded Solid Lipid Nanoparticles for Intranasal Drug Delivery”. AAPS PharmSciTech (2016); 17(6):1353 - 1365. 32. Ahmed M Ali, Adel A. Ali and Ibrahim A. Magrabi., "Clozapine-carboxylic acid plasticized co-amorphous dispersions: Preparation, characterization and solution stability evaluation”. Acta Pharm. (2015): 65, 133 - 146. 33. Randa M Zaki, Adel A. Ali, Shahira F El-Menshawi and Ahmed Abdel Bary., “Formulation and in vitro evaluation of diacerein loaded niosomes”. Int J Pharm Pharm Sci. (2014); 6(2):515 - 521. 34. Adel A. Ali and Ossama M. Sayed., “Development and characterization of ketorolac tromethamine osmotic pump tablets”. Journal of Drug Delivery Science and Technology., (2013). 23 (3), 275 - 281. 35. Ossama M. Sayed, Adel A. Ali, Moahmmed A. El-Nabarawi and Ahmed Abdel Bary., “Comparative pharmacokinetic study of two prokinetic drugs in the form of buccal gels against their market products”. International Journal of Drug Delivery., (2013). Vol 5 Issue 3. 36. Adel A. Ali and Ossama M. Sayed., “Preparation and characterization of mosapride citrate inclusion complexes with natural and synthetic cyclodextrins”. Pharm Dev Technol., (Oct 2013), Vol. 18, No. 5, Pages 1042 - 1050. 37. Adel A. Ali and Ahmed M Ali., “Optimization of propranolol HCl release kinetics from press coated sustained release tablets”. Pharm Dev Technol., (Oct 2013), Vol. 18, No. 5, Pages 1238 - 1246. 38. Randa M. Zaki, Adel A. Ali, Shahira F. El-Menshawi and Ahmed Abdel Bary., “Effect of binary and ternary solid dispersions prepared by fusion method on the dissolution of poorly water soluble diacerein”. International Journal of Drug Delivery., (2013). Vol 5 Issue 1; 99-109. 39. Rasha M. Kharshoum and Adel A. Ali., “Development of Sublingual tablets of Bisoprolol Hemifumarate/ Hydroxypropyl β-Cyclodextrin Complex for Potential treatment of Angina Pectoris”. International Journal of Drug Delivery., (2012) Vol 4 Issue 4, 484-491. 40. Ahmed Abd Elbary, Adel A. Ali and Heba M. Aboud., “Enhanced dissolution of meloxicam from orodispersible tablets prepared by different methods”. Bulletin of Faculty of Pharmacy, Cairo University, (December 2012), Volume 50, Issue 2, Pages 89 - 97. 41. H.M. Aboud, Adel A. Ali and A. Abd Elbary., “Formulation and optimization of tenoxicam orodispersible tablets by solid deposition technique”. Journal of Drug Delivery Science and Technology., (2012). 22 (6) 555 - 561. 42. Sara S.E. M. Megahed, Sadia A Tayel, Mohamed E.A. Abdelrahim, Adel A. Ali, Mohamed H Meabed., “Role of L-Carnitine in Treatment of β-Thalassemia Major Disease”. Journal of Pediatric Sciences. 2011; 3 (3): e91. روابط أخري: Researchgate Google Scholar ORCID Facebook
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